A couple of weeks ago (back when we could stand next to each other in our office), Janet Bill, our Director of Operations, who is also a qualified Nurse, explained what you can use instead of hand sanitiser, if you can't get hold of it in shops. #COVID19https://t.co/W3JjtLZy9R
A new type of gene therapy devised by Professor Nicholas Mazarakis, head of Gene Therapy at the Division of Brain Sciences at London’s Imperial College, has revealed results of its first human tests in The Lancet.
The therapy, designed to treat Parkinson’s disease, delivers 3 genes into the area of the brain responsible for controlling movement, the striatum, using a modified virus which is closely related to HIV. The idea is that the genes will boost the body’s production of the chemical dopamine, in which Parkinson’s sufferers are deficient. The therapy hopes to offer a long-term solution which will stimulate ongoing dopamine production in a different group of cells.
The treatment was first tested on rats and then primates, with surprising results, enabling movement in monkeys that had been disabled before treatment commenced. 15 trial participants were selected for the tests – 12 from France and 3 from the UK – all with advanced Parkinson’s disease. The results show that participant’s scores on movement assessment tests increased by an average of 30%, with results sustained over a 4 year follow up. Scans over this period revealed that participant’s brains were continuing to produce dopamine.
More extensive trials will take place once the delivery method and dose has been optimised by researchers.
Researchers from the Yale School of Public Health have discovered a link between cold weather and risk of stroke – the study results showed that cooler temperatures and variation in temperature meant people were more likely to suffer a fatal stroke.
Research recently carried out in Leicester indicates that folic acid could be beneficial in the treatment of Parkinson’s disease. The research has received coverage on ITV and has also been published in the journal Nature.
Research carried out by the French National Institute of Health and Medical Research has shown that older women with naturally high levels of oestrogen who also suffer from diabetes are more likely to go on to develop dementia.
You might think the choice of living at home is a basic right of any individual – this is true in the majority of cases – but when faced with the impacts of Dementia this choice, for many, can only be achieved with a financial contribution from your local authority.
Scientists at the MRC Centre for Developmental and Biomedical Genetics (CDBG) and the Sheffield Institute of Translational Neuroscience (SITraN) at the University of Sheffield have discovered a new protein which could be key in the fight against Parkinson’s.
Health Ministers meeting for the G8 summit in London have announced their commitment to finding a treatment or cure for dementia as soon as 2025, with the UK announcing it aims to increase research funding to £132m by 2025.
A recent major NHS study by Public Health England has shown that class divisions affect people’s access to the type of palliative care they desire. The research showed that those who are married are more likely to have the option of spending their final days at home, surrounded by their families, whilst those who are single or divorced are more likely to die in hospital.